Troutman Lab

From left: Michael Kotliar, Mohammed Haroon, Amelia Pearson, Yusuf Barudi, Ty Troutman, and Jihye Kang

We study how macrophages and other mononuclear phagocytes regulate health and disease.

Our research is motivated by the urgent need to understand how these cells shape immune responses in chronic digestive and allergic diseases. These diseases affect millions worldwide.

We integrate epigenomic and transcriptomic profiling of highly purified cell populations from healthy and diseased tissues to uncover regulatory mechanisms that govern macrophage identity and function.Our work has revealed transcriptional programs controlling hepatic macrophage behaviors, niche specification, and cross-talk with parenchymal and non-parenchymal liver cells. We strive to publish our results in high-impact journals (Nature Immunology, 2023 and Immunity, 2020) and make our data and tools available to support the mechanistic studies of others across the field.

Find us!

The Troutman lab is housed in the Division of Allergy and Immunology at Cincinnati Children’s Hospital Medical Center. We are also part of the Center for Inflammation and Tolerance and the Department of Pediatrics in the University of Cincinnati College of Medicine.

Cincinnati Children’s Hospital Medical Center
Division of Allergy and Immunology
240 Albert Sabin Way
Building S, S6.540
Cincinnati, OH 45229